Претрага
162 items
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Laboratory Testing of Nanosilica- Reinforced Silicate and Polyacrylamide Gels
Irina Zahirovic, Dušan Danilović, Milica Šuput Vranjin, Miloš Tripković. "Laboratory Testing of Nanosilica- Reinforced Silicate and Polyacrylamide Gels" in SPE Journal (2023)
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Numerical modeling of Selanac debris flow propagation using SPH code
The Selanac debris flow is a very huge event triggered after extreme rainfall caused by Cyclone Tamara activity in the Republic of Serbia in May 2014. The Selanac case study was already modelling in different programs using Voellmy rheology assumptions like RAMMS software. In this paper research are focusing particularly on the process of debris flowing from initiation zone to main deposition area using Geoflow SPH two-phase model considering frictional rheology law. Main rheological parameters are back-calculated using also ...... Journal of Fluid Mechanics 199 (1): 177-215. Takahashi, T. (2007). ‘’Debris Flow: Mechanics, Prediction and Countermeasures’’. Annual Review of Fluid Mechanics 13 (1): 57-77. Zienkiewicz, O.C., Shiomi, T. (1984). ‘’Dynamic behavior of saturated porous media; The generalized Biot formulation and its ...
... found very suitable in different parts of fluid mechanics. Its main difference from other most used methods like finite element and finite difference methods, is in absence of numerical grid, and while mass is presented with particles of solid and fluid phase. Each particle has information about ...
... Debris flows occur usually after saturated, mainly poorly sorted material, started to flow down the slope as a result of motion of solid and fluid phase. Different mechanisms, rheological and numerical models are used in this area of research. Generally, there are mainly two groups of models ...Jelka Krušić, Biljana Abolmasov, Miloš Marjanović, Manuel Pastor, Saeid M. Tayyebi . "Numerical modeling of Selanac debris flow propagation using SPH code" in SCG-XIII International Symposium on Landslides. Cartagena, Colombia- February 22-26, 2021, International Society for Soil Mechanics And Geotechnical Engineering (2021)
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Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach
Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...... 2 of 19 investigation, the role of the formulation scientist becomes crucial to implement advanced formulation strategies early in development processes [2]. However, many attempts under- achieve to overcome poor solubility due to the selection of formulation strategy driven by researchers’ experience ...
... select a formulation strategy based on physicochemical properties of DK-I-60-3 in order to enhance bioavailability after oral administration. As a first step, preformulation studies were designed to obtain insight into the key properties of DK-I-60-3, which would guide further stages of formulation devel- ...
... conducted after oral administration of nanocrystal formulation F5 and corresponding coarse suspension with the same qualitative and quan- titative content (S5) in fasted and fed state. In fasted group, food intake was restricted 10 h before and 4 h after formulation administration, while water was provided ad ...Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach" in Pharmaceutics, MDPI, Basel, Switzerland (2021). https://doi.org/10.3390/pharmaceutics13081188
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Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study
Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...... promising formulation strategy to improve the Pyrazoloquinolinone bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7-methoxy-2-(4-methoxy-d3-phenyl)- Nanocry“?ls 2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and Š:ŽŽŽŽng ...
... undissolved particles would not contribute significantly to the tonicity of the formulation. Therefore, the concen- tration of lyoprotectants and bulking agent was initially adjusted to achieve the isotonic formulation. Nanosuspensions were freeze-dried by the lyophilization-1 and the results of ...
... The conditions for primary drying also depend on this parameter. In this lyophilization phase, the temperature of the formulation should be kept below the critical formulation temperature (CFT). At this temperature, the internal morphology of the product begins to change, resulting in significant ...Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study" in European Journal of Pharmaceutical Sciences, Elsevier BV (2023). https://doi.org/10.1016/j.ejps.2023.106557
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Mitigating hydrate formation in onshore gas wells: A case study on optimization techniques and prevention
Gas wells, particularly those situated onshore, play a vital role in the global energy sector by supplying a significant portion of natural gas. However, operational challenges, notably gas hydrate formation, pose substantial issues, leading to complications such as flowline blockages and unexpected well shutdowns. Gas hydrates, crystalline structures resembling ice, ...Gas Well, Gas Hydrate Formation, Well Modeling, Well Performance Optimization, Choke Position Adjustments, Methanol InjectionMilica Ješić, Bojan Martinović, Stefan Stančić, Miroslav Crnogorac, Dušan Danilović. "Mitigating hydrate formation in onshore gas wells: A case study on optimization techniques and prevention" in Underground Mining Engineering, Beograd : Rudarsko-geološki fakultet (2023)
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Значај петрографске анализе флуидних инклузија
Стефан Петровић, Милош Велојић (2022)У раду је истакнут значај петрографске анализе током истраживања флуидних инклузија и приказане могућности ове методе на примерима неких од карактеристичних петрографских појава из различитих минерала. Петрографска анализа је први корак у испитивању флуидних инклузија. Правилно спроведена, петрографска анализа омогућава одређивање генетске везе флуидних инклузија и минерала домаћина, препознавање карактеристика флуидних инклузија и релевантну интерпретацију података из наредних корака истраживања. Петрографском анализом се дефинишу: а) дистрибуција флуидних инклузија у минералу; б) облик, величина и фазни састав флуидних инклузија; в) групације ...Стефан Петровић, Милош Велојић. "Значај петрографске анализе флуидних инклузија " in Записници српског геолошког друштва, Српско геолошко друштво, Београд (2022)
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Curcumin nanonization using an alternative small-scale production unit: selection of proper stabilizer applying basic physicochemical consideration and biological activity assessment of nanocrystals
Ines Nikolić, Jelena Antić-Stanković, Dragana Božić, Danijela Ranđelović, Bojan Marković, Dominique Jasmin Lunter, Aleksandar Kremenović, Miroslav Savić, Snežana Savić (2020)As the number of poorly soluble drugs is increasing, nanocrystals have become very interesting due to wide range of application possibilities. Curcumin was used as a model active ingredient in this work. Even though it has many proven positive effects, due to its physicochemical issues, its possibilities have not been fully exploited. The goal of this work was to select optimal conditions for a top-down method for curcumin nanosuspension production, and to perform their comprehensive characterization applying complementary methodologies: ...Ines Nikolić, Jelena Antić-Stanković, Dragana Božić, Danijela Ranđelović, Bojan Marković, Dominique Jasmin Lunter, Aleksandar Kremenović, Miroslav Savić, Snežana Savić. "Curcumin nanonization using an alternative small-scale production unit: selection of proper stabilizer applying basic physicochemical consideration and biological activity assessment of nanocrystals" in Review on advanced materials science, Walter de Gruyter GmbH (2020). https://doi.org/10.1515/rams-2020-0043
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Fluid Evolution of the Čukaru Peki Cu-Au Porphyry System (East Serbia) inferred from a fluid inclusion study
Borska metalogenetska zona, Timočki magmatski kompleks, fluidne inkluzije, porfirska ležišta bakra, masivni sulfidi, slani rastvori, ključanje fluidaVelojić Miloš, Jelenković Rade, Cvetković Vladica. "Fluid Evolution of the Čukaru Peki Cu-Au Porphyry System (East Serbia) inferred from a fluid inclusion study" in Geologia Croatica, Croatian Geological Survey (2020). https://doi.org/10.4154/gc.2020.14
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Uticaj utiskivanja gas-lift gasa na prenos mase i toplote
Branko Grubač (2019)Nakon uvođenja kontinualnog gas-lifta, primećen je porast proizvodnje tečnog naftnog gasa, TNG, u postrojenju za preradu gasa, kao jednog od finalnih proizvoda dobijenog iz fluida gaso kondenzatnih i rastvorenog gasa iz naftnih bušotina. Pretpostavljeno je da se prisustvom gas-lift gasa uspostavlja drugačija ravnoteža faza u odnosu na slučaj bez gaslifta, te da je gas-lift gas stripovao propan i butane iz tečne u parnu fazu, što je dovelo do povećanja prinosa TNG-a. Napravljen je model bušotine koja radi u kontinualnom gas-liftu ...... Sastav parne faze fluida – Poređenje Slučaja #1 i Slučaja #2 Komponenta Bušotina B-1 Bušotina B-2 Bušotina B-3 Slučaj #1 Slučaj #2 Slučaj #1 Slučaj #2 Slučaj #1 Slučaj #2 Fluid sa GL gasom Fluid bez GL gasa Fluid sa GL gasom Fluid bez GL gasa Fluid sa GL gasom Fluid bez GL gasa ...
... proračun razmene toplote fluida u bušotini koja proizvodi u kontinualnom gas-liftu. Proračun razmene toplote obuhvata razmenu toplote između fluida u kezingu (gas-lift gasa) i okoline (zemlje), zatim i razmenu toplote između fluida u tubingu (ležišni fluid) i fluida u kezingu. Na razmenu toplote ...
... ovako opisanom termodinamičkom sistemu, pored pritiska i temperature, utiču i osobine fluida kao što su toplotni kapacitet, sastav fluida, režim strujanja, količina fluida, brzina kretanja fluida, smer kretanja fluida, ali i sama kompozicija bušotine odnosno materijal tubinga, kezinga, hrapavost cevi ...Branko Grubač. Uticaj utiskivanja gas-lift gasa na prenos mase i toplote, Beograd : Rudarsko-geološki fakultet, 2019
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Fluid inclusion study in quartz of the Rudnik Pb-Zn-Cu-Ag skarn deposit, Serbia
Six types of fluid inclusions were identified in three growth zones of hydrothermal quartz from the Rudnik skarn deposit. In the core zone, primary two-phase fluid inclusions of high (type 1) and moderate salinity (type 2) homogenized to liquid between 350-430 °C and 340-420 °C, respectively. Raman analysis revealed that the vapour phases are a CO2-CH4 gas mixture, with a predominance of CO2. The core contains and dispersed vapour-rich fluid inclusions of low salinity (type 3) composed of CO2-CH4-H2S ...Stefan Petrović, Ronald J. Bakker, Vladica Cvetković, Rade Jelenković. "Fluid inclusion study in quartz of the Rudnik Pb-Zn-Cu-Ag skarn deposit, Serbia" in Mineral Resources in a Changing World-17th SGA Biennial Meeting, Zurich, between 28th August and 1st September 2023, Genéve : Society for Geology Applied to Mineral Deposits (2023)
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Convective heat transfer in centrifugal pumps lifted wells: the case of South-Eastern Europe waxy wells
Electric submersible pumps (ESP) are applied in wells where additional energy is needed to ensure discharge of the fluid to the surface through the tubing. At the discharge side of the pump the fluid has bigger velocity, thus the pump induces a forced convection between the fluid and the tubing inner surface. Understanding of convective heat transfer in wellbores and analyses of influential parameters provides a possibility to optimise value of convective heat transfer coefficient in order to avoid ...Bojan Martinovic, Marija Živković, Branko Grubač. "Convective heat transfer in centrifugal pumps lifted wells: the case of South-Eastern Europe waxy wells" in International Journal of Oil, Gas and Coal Technology, Inderscience Publishers (2021). https://doi.org/10.1504/IJOGCT.2021.10043281
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Fluid inclusion systematics in the Okoška gora polymetallic deposit
... Измењено: 2023-10-14 04:27:31 Fluid inclusion systematics in the Okoška gora polymetallic deposit Aleš Šoster, Miloš Velojić, Barbara Potočnik Krajnc, Matej Dolenec Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] Fluid inclusion systematics in the Okoška ...
... veins of transparentquartz intersectvi amethyst (Janez Žavašnik, verbal comm.), suggesting the later's earlier paragenetic p Fluid inclusion systematics A total of 100 fluid inclusions in sphalerite and quartz from five samples of ore were investigated in this study. Both types of quartz form well ...
... between pre-existi and gangue minerals. Sphalerite is honey yellow or dark brown in color and its transparency makesit suitable for fluid inclusion analysis. The fluid inclusions are usually 10-50 umin size, All of the analyzed inclusion liquid-rich and contain about 60—80 % liquid and 20-40 % vapourphase ...Aleš Šoster, Miloš Velojić, Barbara Potočnik Krajnc, Matej Dolenec. "Fluid inclusion systematics in the Okoška gora polymetallic deposit" in 25th meeting of Slovenian geologists, Ljubljana, 2021, Univerza v Ljubljani, Oddelek za geologijo (2021)
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Optimizacija ispirnih fluida za bušenje dirigovanih bušotina
Vukoman Krgović (1994)Vukoman Krgović. Optimizacija ispirnih fluida za bušenje dirigovanih bušotina, Beograd:Rudarsko Geološki Fakultet, 1994
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Hibridni sistem za planiranje i analizu ventilacije rudnika
... neviskoznog fluida. Ovim se potvrđuje Prantlova (Prandtl) ideja po kojoj fluid struji van graničnog sloja upravo kao da je savršen. Razume se, to ne znači da realan fluid postaje neviskozan već znači da se ova konstatacija odnosi na kinematičku sliku strujanja, jer svojstva realnog fluida kao što su: ...
... softvera NISA/3D – FLUID NISA/3D–FLUID (Numerički Integrisani elementi za Analizu 3D Sistema mehanike Fluida) je program konačnih elemenata razvijen i podržavan od EMRC (Engineering Mechanics Research Corporation) za analizu širokog spektra problema koji postoje u mehanici fluida. Pretprocesiranje ...
... primenjenu mehaniku, teoriju aproksimacija, numeričku analizu i računarsku nauku. Računska dinamika fluida (Computational Fluid Dynamics - CFD) omogućava analizu sistema koja se odnosi na procese strujanja fluida i prenosa toplote, a takođe, i uključivanje pojava kao što su na primer hemijske reakcije. CFD ...Nikola Lilić, Ranka Stanković, Ivan Obradović. Hibridni sistem za planiranje i analizu ventilacije rudnika, Rudarsko-geološki fakultet, Univerzitet u Beogradu, 2000
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Uticaj karakteristika ispirnih fluida na pribušotinsku zonu naftnih i gasnih bušotina
Tatjana A. Malbašić (2016)Tatjana A. Malbašić. Uticaj karakteristika ispirnih fluida na pribušotinsku zonu naftnih i gasnih bušotina, Beograd:Rudarsko-geološki fakultet, 2016
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Geohemijske karakteristike slojnih fluida naftnih, naftno-gasnih ležišta jugoistočnog dela Panonskog basena i korišćenje nekih geohemijskih pokazatelja pri pronalaženju i istraživanju ležišta nafte i gasa
Miodrag Šarković (1972)Miodrag Šarković. Geohemijske karakteristike slojnih fluida naftnih, naftno-gasnih ležišta jugoistočnog dela Panonskog basena i korišćenje nekih geohemijskih pokazatelja pri pronalaženju i istraživanju ležišta nafte i gasa, Novi Sad:, 1972
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Remontni radovi u bušotini sa dubinskom pumpom
Jovana Milošević (2024)Remontni i stimulativni radovi u naftnom inženjerstvu su radovi koji se primenjuju na bušotinama koje su već u proizvodnji ili potencijalno proizvodnim bušotinama, i u zavisnosti od toga imaju različitu svrhu. Remontni radovi predstavljaju sve radove koji su ograničeni na kanal bušotine, dok se stimulativni radovi odnose pribušotinsku zonu.U prvom slučaju remontni i stimulativni radovi kod proizvodnih bušotina služe za otklanjanje problema i povećavanje proizvodnje bušotine. Dok u drugom slučaju, kod potencijalnih bušotina su ovi radovi namenjeni završnim obradama ...... radnim fluidom u bušotini 19 - potiskuje što dublje izreagovanu kiselinu u porni prostor stene - obnavljanje vodokvašljivosti stene U naftnim bušotinama se kao potisni fluid koristi sirova nafta, dizel ulje,15 %-na HCI ili vodeni rastvor NH4CI. U gasnim bušotinama se kao potisni fluid koristi ...
... toranj i radna postolja (rost), sistem koturača, kočnica, sistem za cirkulaciju radnim fluidom ( pumpe, isplačnu glavu, isplačno crevo, čelični bazeni za isplaku), uređaji za pravljenje ı mešanje radnih fluida, sistem za rotaciju ( rotaciona glava, rotacioni sto, radna šipka), oprema na podištu ...
... koja predstavljaju filter barijeru pesku i sprečavaju njegov ulazak u bušotinu, propuštajući samo fluid iz ležišta. Najbitnije kod ugradnje gravel pack sistema su čistoća bušotine, radnog fluida ı površinske opreme kao ı gusto pakovanje gravela (šljunka). Gravel pack oprema se sastoji od proizvodne ...Jovana Milošević . Remontni radovi u bušotini sa dubinskom pumpom, 2024
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Upravljanje procesom razrade i eksploatacije ležišta ugljovodoničnih fluida
Vesna Karović Maričić (2006)Vesna Karović Maričić. Upravljanje procesom razrade i eksploatacije ležišta ugljovodoničnih fluida, Beograd:Rudarsko Geološki Fakultet, 2006
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Model čišćenja gasovoda i pulpovoda tokom fluida
Batalović Veselin (2010)Batalović Veselin. "Model čišćenja gasovoda i pulpovoda tokom fluida" in Tehnika 61 no. 1 (2010): 1-6
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The analysis of the geothermal energy capacity for power generation in Serbia
Jana Stojković, Goran Marinković, Petar Papić, Mihailo Milivojević, Maja Todorović, Marina Ćuk (2013)... resources. Their correct interpretation based on exploratory drilling data may give accurate estimates of fluid temperature in a geothermal reservoir. They are also useful in monitoring, because variation of a geothermometer during the geothermal fluid abstraction indi- cates a change in the reservoir itself ...
... separated from the closed loop working fluid used in the turbine by a heat exchanger. The hot water gives up its heat in the heat exchanger to a working fluid with a low boiling point and high vapour pressure at low temperatures when compared to steam. The working fluid is usually ammonia or some organic ...
... lower fluid temperatures, chalcedony is used, which controls the amount of dis- solved silicon. Many geothermometers have been developed, of which the quartz geothermo- meter for thermal water most frequently uses the formula [7]: t [ C] (SiO2 � � � � 1309 519 27315 [ . log )] . (1) Fluid temperatures ...Jana Stojković, Goran Marinković, Petar Papić, Mihailo Milivojević, Maja Todorović, Marina Ćuk. "The analysis of the geothermal energy capacity for power generation in Serbia" in Thermal Science, National Library of Serbia (2013). https://doi.org/10.2298/TSCI120215033S