Претрага
241 items
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Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach
Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...... Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook ...
... Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach | Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook ...
... the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach Jelena R. Mitrović 1, Branka Divović-Matović 2, Daniel E. Knutson 3 , Jelena B. Ðoković 1, Aleksandar Kremenović 4 , Vladimir D. Dobričić 5, Danijela V. Randjelović 6, ...Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach" in Pharmaceutics, MDPI, Basel, Switzerland (2021). https://doi.org/10.3390/pharmaceutics13081188
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Mineraloška i kinetička proučavanja aluminatnog cementa
Branko Matović (1998)Branko Matović. Mineraloška i kinetička proučavanja aluminatnog cementa, Beograd:Rudarsko-geološki fakultet, 1998
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Sinteza vatrostalnog aluminatnog cementa i proučavanje njegove hidratacije i termičke stabilnosti
Branko Matović (1993)Branko Matović. Sinteza vatrostalnog aluminatnog cementa i proučavanje njegove hidratacije i termičke stabilnosti, Beograd:Rudarsko-geološki fakultet, 1993
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Petrografske karakteristike dacita i uticaj na čvrstoću na pritisak
Matović Vesna, Srećković-Batoćanin Danica, Matović Nenad, Munjas Branko. "Petrografske karakteristike dacita i uticaj na čvrstoću na pritisak" in Konferencija Savremeni materijali i konstrukcije sa regulativom, Beograd :Društvo za ispitivanje i istraživanje materijala i konstrukcije Srbije (2016): 115-123
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Granite resistance to atmospheric attack – test of accelerated weathering
Matović Vesna, Erić Suzana, Đokić Olivera, Matović Nenad, Munjas Branko. "Granite resistance to atmospheric attack – test of accelerated weathering" in Geoekologija XXI vijeka / Međunarodni simpozijum - Geoeco 2010, Žabljak-Nikšić, 21-24 Septembar 2010. godine Crna Gora - Montenegro, Žabljak-Nikšić, Montenegro:Filozofski fakultet (2010): 529-535
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Технички услови квалитета туцаника за железничке пруге – Национални и Европски критеријуми
Đokić Olivera, Matović Vesna, Gašić Ranko, Milićević Vladimir, Matović Nenad, Munjas Branko. "Технички услови квалитета туцаника за железничке пруге – Национални и Европски критеријуми" in Грађевински материјали у савременом градитељству. Зборник радова Национална конференција са међународним учешћем, 19.јун 2015. године, Београд, :Друштво за испитивање и истраживање материјала и конструкција Србије (2015): 149-157
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Petrologic and technical properties of the Triassic limestone from the open pit Rupeljevo
Avramović Nikola, Matović Vesna, Gajić Violeta, Srećković Batoćanin Danica, Matović Nenad, Munjas Branko (2012)Avramović Nikola, Matović Vesna, Gajić Violeta, Srećković Batoćanin Danica, Matović Nenad, Munjas Branko. "Petrologic and technical properties of the Triassic limestone from the open pit Rupeljevo" in Proceedings / 2nd International Conference Harmony of Nature and Spirituality in Stone, 15-16 March 2012, Kragujevac, Belgrade:Stone Studio Association (2012): 97-107
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Basic rocks from the Povlen mountain as a building material
Srećković Batoćanin Danica, Savić Marija, Matović Nenad, Munjas Branko, Mladenović Mališa. "Basic rocks from the Povlen mountain as a building material" in Proceedings, 1st International Conference “HARMONY OF NATURE AND SPIRITUALITY IN STONE”, 17-18 March 2011, Kragujevac, Kragujevac:Stone Studio Association (2011): 185-199
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Phase, morphological and statistical analysis of urinary stones from Serbian patients.
Mirković Miljana, Dosen Ana, Matović Branko, Erić Suzana, Vulić Predrag, Rosić Aleksandra. "Phase, morphological and statistical analysis of urinary stones from Serbian patients." in Seventeenth Young Researchers Conference, Materials Science and Engineering. December 5-7, 2018, Belgrade, Serbia, Program and the Book of Abstracts (2018): 21
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Preparation and characterization of chrome doped sphene pigments prepared via precursor mechanochemical activation
Pantić Jelena, Prekajski Marija, Dramićanin Miroslav, Abazović Nadica, Vuković Nikola, Kremenović Aleksandar, Matović Branko (2013)Pantić Jelena, Prekajski Marija, Dramićanin Miroslav, Abazović Nadica, Vuković Nikola, Kremenović Aleksandar, Matović Branko. "Preparation and characterization of chrome doped sphene pigments prepared via precursor mechanochemical activation" in Journal of Alloys and Compounds 579, :Elsevier B.V. (2013): 290-294
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Application of the Final Flotation Waste for Obtaining the Glass-ceramic Materials
Mira Cocić, Mihovil Logar, Suzana Erić, Viša Tasić, Snežana Dević, Saša Cocić, Branko Matović (2017)Mira Cocić, Mihovil Logar, Suzana Erić, Viša Tasić, Snežana Dević, Saša Cocić, Branko Matović. "Application of the Final Flotation Waste for Obtaining the Glass-ceramic Materials" in Science of Sintering 49, Belgrade:International Institute for the Science of Sintering (2017): 431-433
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Phase and microstructural study of urinary stones
In this paper we present the phase and morphological characteristics of urinary stones from Serbian patients. The study included for the first time the determination of the phase composition and a statistical analysis of the presence of different types of urinary stones in both men and women in Serbia. The main goal of study was representation of collected data for the first time. For past three years, more than 600 samples were collected from Serbian patients. The phase composition ...бубрежно камење, фазни састав, статистика, рендгенска дифракција праха, скенирајућа електронска микроскопијаMiljana Mirković, Anja Dosen, Suzana Erić, Predrag Vulić, Branko Matović, Aleksandra Rosić. "Phase and microstructural study of urinary stones" in Microchemical Journal, Elsevier BV (2019). https://doi.org/10.1016/j.microc.2019.104429
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Nanocrystaline solid solution CeO 2-Bi 2O 3
Prekajski Marija, Dohcevic-Mitrović Zorana, Radović Marko, Babić Biljana, Pantić Jelena, Kremenović Aleksandar, Matović Branko (2012)Prekajski Marija, Dohcevic-Mitrović Zorana, Radović Marko, Babić Biljana, Pantić Jelena, Kremenović Aleksandar, Matović Branko. "Nanocrystaline solid solution CeO 2-Bi 2O 3" in Journal of the European Ceramic Society 9 no. 32, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND:Elsevier Sci Ltd (2012): 1983-1987. https://doi.org/10.1016/j.jeurceramsoc.2011.12
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Thermal stability of Ce1-xBixO2-delta (x = 0.1-0.5) solid solution
Prekajski Marija, Fruth Viktor, Andronescu Cristian, Trandafilovic Lidija V., Pantić Jelena, Kremenović Aleksandar, Matović Branko (2013)Prekajski Marija, Fruth Viktor, Andronescu Cristian, Trandafilovic Lidija V., Pantić Jelena, Kremenović Aleksandar, Matović Branko. "Thermal stability of Ce1-xBixO2-delta (x = 0.1-0.5) solid solution" in Journal of Alloys and Compounds no. 578, PO BOX 564, 1001 LAUSANNE, SWITZERLAND:Elesevier Science Inc (2013): 26-31. https://doi.org/10.1016/jjallcom.2013.05.006
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Structural, Morphological and Electrical Properties of Multi-Doped Calcium Phosphate Materials as Solid Electrolytes for Intermediate Temperature Solid Oxide Fuel Cells
Mirković M. Miljana, Došen, M. Anja, Erić P. Suzana, Stojmenović D. Marija, Matović Z. Branko, Rosić A. Aleksandra (2018)Mirković M. Miljana, Došen, M. Anja, Erić P. Suzana, Stojmenović D. Marija, Matović Z. Branko, Rosić A. Aleksandra. "Structural, Morphological and Electrical Properties of Multi-Doped Calcium Phosphate Materials as Solid Electrolytes for Intermediate Temperature Solid Oxide Fuel Cells" in Science of Sintering 50 no. 1, Beograd:International Institute for the Science of Sintering, Belgrade, Serbia (IISS) (2018): 95-109. https://doi.org/10.2298/SOS1801095M
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Structural, Morphological and Electrical Properties of Multi-Doped Calcium Phosphate Materials as Solid Electrolytes for Intermediate Temperature Solid Oxide Fuel Cells
Mirković Miljana M., Došen Anja M., Erić Suzana P., Stojmenović, Marija D., Matović Branko Z., Rosić Aleksandra A. (2018)Mirković Miljana M., Došen Anja M., Erić Suzana P., Stojmenović, Marija D., Matović Branko Z., Rosić Aleksandra A.. "Structural, Morphological and Electrical Properties of Multi-Doped Calcium Phosphate Materials as Solid Electrolytes for Intermediate Temperature Solid Oxide Fuel Cells" in Science of Sintering 1 no. 50, Beograd:Međunarodni Institut za nauku o sinterovanju (2018): 95-109. https://doi.org/https://doi.org/10.2298/SOS180
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Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study
Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...... license (http://creativecommons.org/licenses/by- nc-nd/4.0/). J.R. Mitrović et al. with their other psychomotor or anticonvulsant effects (Divović Matović et al., 2022). To increase metabolic stability and bioavailability, deuterated analogues, including DK-I-56-1 (7-methoxy-2-(4-methox- y- ...
... Physico-chemical characterization of anhydrous D-mannitol. J. Therm. Anal. Calorim. 95 (3), 871–876. https://doi.org/10.1007/510973-008-9384-5, Divović Matović, B., Knutson, D., Mitrović, J., Stevanović, V., Stanojević, B., Savić, S., 'Cook, J.M., Savić, M.M., 2022. Behavioural interaction of pyrazo ...
... freezing rate, and a noncrystallizing cosolute. J. Pharm. Sci. 87 (8), 931–935. https://doi.org/10.1021/js980001d. 'Knutson, D.E., Kodali, R., Divović, B., Treven, M., Stephen, M.R., Zahn, N.M., Dobričić, V., Huber, A.T., Meirelles, M.A., Verma, R.S., et al., 2018. Design and synthesis of novel ...Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study" in European Journal of Pharmaceutical Sciences, Elsevier BV (2023). https://doi.org/10.1016/j.ejps.2023.106557
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Synthesis and characterization of high-pressure and high-temperature sphene (CaTiSiO5)
Jelena Pantić, Vladimir Urbanovich, Vesna Poharc-Logar, Bojan Jokić, Marija Stojmenović, Aleksandar Kremenović, Branko Matović (2014)Sphene (CaTiSiO5), a calcium titanosilicate ceramic has been prepared from a powder mixture of CaCO3, TiO2 and SiO2 using vibro-milling for homogenization and activation of precursors. During the highpressure and high-temperature synthesis (HPS) process at 4 GPa and 1,200 °C, sphene undergoes into phase transition, from room-temperature phase P21/a to high-temperature phase A2/a. Evidence of that structural phase transition is given in this paper using infrared, Raman spectroscopy and X-ray powder diffraction. Rietveld refinement was employed to get the ...Jelena Pantić, Vladimir Urbanovich, Vesna Poharc-Logar, Bojan Jokić, Marija Stojmenović, Aleksandar Kremenović, Branko Matović. "Synthesis and characterization of high-pressure and high-temperature sphene (CaTiSiO5)" in Physics and Chemistry of Minerals, Springer Science and Business Media LLC (2014). https://doi.org/10.1007/s00269-014-0693-x
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Ситне честице у каменом агрегату за путеве: методологија и значај
Матовић Весна, Росић Александра, Ерић Сузана, Матовић Ненад. "Ситне честице у каменом агрегату за путеве: методологија и значај" in Грађевински календар 47, :Савез грађевинских инжењера Србије (2015): 237-262
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Experimental simulation of chemical weathering of limestone
Erić Suzana, Matović Vesna, Srećković Batoćanin Danica, Matović Nenad. "Experimental simulation of chemical weathering of limestone" in Proceedings / 3rd International Conference Harmony of Nature and Spirituality in Stone, 21-22 March 2013, Kragujevac, Serbia, Belgrade:Stone Studio Association (2013): 147-153