Претрага
181 items
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The influence of Al<sup>3+</sup>ion on porcine pepsin activity<i>in vitro</i>
The in vitro effect of Al3þ ions in the concentration range 1.7·1026M–8.7·1023M on pepsin activity at pH 2, via kinetic parameters and its electrophoretic mobility was evaluated. Kinetic study demonstrated the existence of an activation effect of Al3þ at pH 2 on pepsin molecule. Kinetic analysis with respect to concentrations of haemoglobin showed that Al3þ ions increase the maximal velocity (Vmax) and kcat values rather than apparent affinity for substrate (KS) implying the non-competitive nature of activation which indicated ...... activator concentration that gives a rate equal to half at a saturating concentration of activator, were found to be 8.82 + 0.90 „M, 8.39 + 0.76 „ M, and 8.05 + 0.48 „M respectively. Native PAGE electrophoresis shows the decrease in electrophoretic mobility of pepsin and confirms modification of the ...
... sample of 5 mL of pepsin solution (3:10 M ofin 0.01 M HCI, pH 2), was extensively dialyzed. Solution was placed in dialysis bags (0 mm flat width) with a molecular cut of 12 to 14 kDa (Sigma- Aldrich) and dialysed against 50mL AICI5·6H»O solution (0.01 M pH 2), for 36h at 4"C with gently stirring ...
... Aluminium was found to stimulate the enzyme activity 250 _ APP1(M % of activation »0 | IA ](M) % s | . 0 a 1.7x10 30.7 ' isoj 34x10% 51.0 -| 17x10" 72.8 < | 17x10% 95,7 87%1I0% 135.8 100—- — —— ıI IO 107 107 |[} [AU](M) Figure 1. Relative activity of pepsin in the presence of AP * ions ...Vesna M. Pavelkić, Kristina R. Gopcević, Danijela Z. Krstić, Marija A. Ilić. "The influence of Al3+ion on porcine pepsin activityin vitro" in Journal of Enzyme Inhibition and Medicinal Chemistry, Informa UK Limited (2008). https://doi.org/10.1080/14756360701841095
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Identification of alginite and bituminite in rocks other than coal: results of Round Robin Exercises of the Identification of Dispersed Organic Matter Working Group of the ICCP
Kus J., Araujo C.V., Borrego A.G., Flores D., Hackley P.C., Hámor-Vidó M., Kalaitzidis S., Kommeren C.J., Kwiecińska B., Mastalerz M., Mendonça Filho J.G., Menezes T.R., Misz-Kennan M., Nowak G.J., Petersen H.I., Rallakis D., Suárez-Ruiz I., Sýkorová I., Životić Dragana (2017)Kus J., Araujo C.V., Borrego A.G., Flores D., Hackley P.C., Hámor-Vidó M., Kalaitzidis S., Kommeren C.J., Kwiecińska B., Mastalerz M., Mendonça Filho J.G., Menezes T.R., Misz-Kennan M., Nowak G.J., Petersen H.I., Rallakis D., Suárez-Ruiz I., Sýkorová I., Životić Dragana. "Identification of alginite and bituminite in rocks other than coal: results of Round Robin Exercises of the Identification of Dispersed Organic Matter Working Group of the ICCP" in International Journal of Coal Geology 178, Amsterdam, Netherlands:Elsevier BV (2017): 26-38. https://doi.org/10.1016/j.coal.2017.04.013
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Fission-track constraints on the thermal evolution of the Serbo-Macedonian Massif (south Serbia, southwest Bulgaria and east Macedonia)
Antić, M., Kounov A., Trivic B., Peytcheva I., von Quadt A., Gerdjikov I.. "Fission-track constraints on the thermal evolution of the Serbo-Macedonian Massif (south Serbia, southwest Bulgaria and east Macedonia)" in 10th Swiss Geoscience Meeting, Bern, Switzerland, 16-17 November 2012, Abstract Volume, Bern: (2012): 65-65
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Oligocene shoshonitic rocks of the Rogozna Mts. (Central Balkan Peninsula): evidence of petrogenetic links to the formation of Pb-Zn-Ag ore deposits
Borojević-Šoštarić Sibila, Cvetković Vladica, Neubauer Franz, Palinkaš Ladislav, Bernroider M., Genser Johann (2011)Borojević-Šoštarić Sibila, Cvetković Vladica, Neubauer Franz, Palinkaš Ladislav, Bernroider M., Genser Johann. "Oligocene shoshonitic rocks of the Rogozna Mts. (Central Balkan Peninsula): evidence of petrogenetic links to the formation of Pb-Zn-Ag ore deposits" in Lithos 148 no. 1, Amsterdam, Netherlands:Elsevier (2011): 176-195. https://doi.org/10.1016/j.lithos.2012.05.028
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Adakite-like and Normal Arc Magmas: Distinct Fractionation Paths in the East Serbian Segment of the Balkan-Carpathian Arc
Kolb M., von Quadt Albrecht, Peytcheva Irena, Heinrich C.A., Fowler S.J., Cvetković Vladica. "Adakite-like and Normal Arc Magmas: Distinct Fractionation Paths in the East Serbian Segment of the Balkan-Carpathian Arc" in Journal of Petrology 54 no. 3, Oxford, UK:Oxford University Press (2013): 421-451. https://doi.org/10.1093/petrology/egs072
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Application of novel Zn-ferrite modified glassy carbon paste electrode as a sensor for determination of Cd(II) in waste water
Stanković Dalibor M, Skrivanj Sandra, Savić Nenad, Nikolić Aleksandar, Vulić Predrag, Manojlović Dragan (2014)Stanković Dalibor M, Skrivanj Sandra, Savić Nenad, Nikolić Aleksandar, Vulić Predrag, Manojlović Dragan. "Application of novel Zn-ferrite modified glassy carbon paste electrode as a sensor for determination of Cd(II) in waste water" in Electroanalysis 26 no. 7, Hoboken, NJ:John Wiley & Sons (2014): 1536-1543. https://doi.org/10.1002/elan.201400095
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Phase relations and physical indicators of municipal waste from old landfills in Serbia
Due to certain similarities of municipal waste and soil, usually for the determination of basic parameters of physical state, laboratory and field tests which are common in geotechnical investigations are used. It is often to construct an apparatus for special purpose to perform some specific laboratory and field tests. Therefore, different values of indicators of municipal waste physical state can be found in the literature. The basic reasons should be found in different definitions and methods that researchers use ...municipal waste, moisture content, unit weight, specific gravity, grain size distribution, porosityGeneral Computer Science... Unit Relations Unit weight Y kN/m) Y=W/V=(I+w) ·Ya Void ratio e mš/m* e= V /V, = | ___I-n Unit weight W a of solid A kN/m* E i ——— particles Vs 1-n 'Volume water v m*/m* v= V Zw.J0 content -% V Yw Volume gas a m*/m* a _&_ n_w content -% a Saturation g m*/m* S =&=X degree ii -% ii Vp ...
... taken was 1.0 – 12.0 m), values ranged in a wide interval of y = 9.5 — 17.6 108 kN/m, It can be seen that the values are in the domain of possible values of waste unit weight that correspond medium to well compacted waste (Figure 6). unit weighty (kN/n») unit weight y (KN/m*) 15 20 5 0+ E ...
... Ikodinović, Jovana M Janković, Tina D Đurić Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] Phase relations and physical indicators of municipal waste from old landfills in Serbia | Dragoslav R Rakić, Irena G Basarić Ikodinović, Jovana M Janković, Tina D Đurić ...Dragoslav R Rakić, Irena G Basarić Ikodinović, Jovana M Janković, Tina D Đurić. "Phase relations and physical indicators of municipal waste from old landfills in Serbia" in Japanese Geotechnical Society Special Publication, The Japanese Geotechnical Society (2021). https://doi.org/10.3208/jgssp.v09.cpeg016
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Implemented Stage Fracturing Technique To Improve Oil Production In Nubian Sandstone Of North Gialo, Libya
Fandi Emad I. M., Leković Branko, Gazal Badees, Elhaddad Elnori, Al Saghr Abdulbaset. "Implemented Stage Fracturing Technique To Improve Oil Production In Nubian Sandstone Of North Gialo, Libya" in Acta Montanistica Slovaca 23 no. 3, Košice:Faculty of Mining, Ecology, Process Control and Geotechnologies (FBERG), Technical University of Kosice (2018): 245-259
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Implemented Stage Fracturing Technique To Improve Oil Production In Nubian Sandstone Of North Gialo, Libya
Fandi Emad I. M., Leković Branko, Gazal Badees, Elhaddad Elnori, Al Saghr Abdulbaset. "Implemented Stage Fracturing Technique To Improve Oil Production In Nubian Sandstone Of North Gialo, Libya" in Acta Montanistica Slovaca 23 no. 3, Košice:Faculty of Mining, Ecology, Process Control and Geotechnologies (FBERG), Technical University of Kosice (2018): 245-259
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Back-arc underplating provided crustal accretion affecting topography and sedimentation in the Adria microplate
Paolo Mancinelli, Vittorio Scisciani, Cristina Pauselli, Gérard M. Stampfli, Fabio Speranza, Ivana Vasiljević (2021)Supported by evidence of deep crustal sources for the observed magnetic anomalies in Central Italy and by outcropping gabbros in the Croatian archipelago, we model the observed gravity and magnetic anomalies in the Central Adriatic Sea and surroundings. We suggest that the major magnetic anomalies in the area are related to a wide underplating and propose that this volume represents the first stage of the back-arc Adria continental breakup in Early Permian times. During the Palaeotethys-Adria collision, underplating has ...Paolo Mancinelli, Vittorio Scisciani, Cristina Pauselli, Gérard M. Stampfli, Fabio Speranza, Ivana Vasiljević. "Back-arc underplating provided crustal accretion affecting topography and sedimentation in the Adria microplate" in Marine and Petroleum Geology, Elsevier Ltd. (2021). https://doi.org/10.1016/j.marpetgeo.2021.105470
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Dating intrusion and cooling of Cenozoic granitoids in the Dinarides of Southern Serbia and discussion of the geodynamic setting of Paleocene-Miocene magmatism in the Balkan Peninsula.
Schefer S., Cvetković Vladica, Fügenschuh Bernhard, Kounov A., Ovtcharova M., Schaltegger U., Schmid S. (2010)Schefer S., Cvetković Vladica, Fügenschuh Bernhard, Kounov A., Ovtcharova M., Schaltegger U., Schmid S.. "Dating intrusion and cooling of Cenozoic granitoids in the Dinarides of Southern Serbia and discussion of the geodynamic setting of Paleocene-Miocene magmatism in the Balkan Peninsula." in Geophysical Research Abstracts 12, Vienna, Austria:EGU (2010): 2530-2530
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Calculative image analysis of oxidation induced food colour changes
L. Pezo, M. Pavlović, S. Ostojić, Kovačević Olgica, Zlatanović Snežana, Ilić Marija, Gvozdenović Jasna (2010)L. Pezo, M. Pavlović, S. Ostojić, Kovačević Olgica, Zlatanović Snežana, Ilić Marija, Gvozdenović Jasna. "Calculative image analysis of oxidation induced food colour changes" in Rizici i eko -bezbednost u postmodernom ambijentu -Internacionalna konferencija, septembar 19-12 jun, Novi Pazar, Novi Pazar:Državni univerzitet u Novom Pazaru (DUNP) (2010): 125-131
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The recent fault kinematics in the westernmost part of the Getic nappe system (Eastern Serbia): Evidence from fault slip and focal mechanism data
Mladenović Ana, Trivić Branislav, Antić M., Cvetković Vladica, Pavlović Radmila, Radovanović S., Fügenschuh Bernhard (2014)Mladenović Ana, Trivić Branislav, Antić M., Cvetković Vladica, Pavlović Radmila, Radovanović S., Fügenschuh Bernhard. "The recent fault kinematics in the westernmost part of the Getic nappe system (Eastern Serbia): Evidence from fault slip and focal mechanism data" in Geologica Carpathica 65 no. 2, Bratislava, Slovak Republic:Veda, Publishing House of the Slovak Academy of Sciences (2014): 147-161. https://doi.org/10.2478/geoca-2014-0010
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An arid phase in the Internal Dinarides during the early to middle Miocene: Inferences from Mg-clays in the Pranjani Basin (Serbia)
N. Andrić-Tomašević, V. Simić, O. Mandic, D. Životić, M. Suárez, E. García-Romero. "An arid phase in the Internal Dinarides during the early to middle Miocene: Inferences from Mg-clays in the Pranjani Basin (Serbia)" in Palaeogeography, Palaeoclimatology, Palaeoecology, Elsevier BV (2020). https://doi.org/10.1016/j.palaeo.2020.110145
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Reprint of Petrological and organic geochemical properties of lignite from the Kolubara and Kostolac basins, Serbia: implication on grindability index
Životić Dragana, Bechtel A., Sachsenhofer R., Gratzer R., Radić D., Obradović M., Stojanović Ksenija (2015)Životić Dragana, Bechtel A., Sachsenhofer R., Gratzer R., Radić D., Obradović M., Stojanović Ksenija. "Reprint of Petrological and organic geochemical properties of lignite from the Kolubara and Kostolac basins, Serbia: implication on grindability index" in International Journal of Coal Geology 157, Amsterdam, Netherlands:Elsevier BV (2015): 165-183. https://doi.org/10.1016/j.coal.2014.07.004
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Geochemistry, Sr–Nd–Pb isotopes and geochronology of amphibole- and mica-bearing lamprophyres in northwestern Iran: Implications for mantle wedge heterogeneity in a palaeo-subduction zone
M. Aghazadeh, Д. Прелевић, Z. Badrzadeh, E. Braschi, P. van den Bogaard, S. Conticelli. "Geochemistry, Sr–Nd–Pb isotopes and geochronology of amphibole- and mica-bearing lamprophyres in northwestern Iran: Implications for mantle wedge heterogeneity in a palaeo-subduction zone" in Lithos 216-217 (2015): 352-369. https://doi.org/doi.org/10.1016/j.lithos.2015.
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Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach
Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...... Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] Overcoming the Low Oral ...
... Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić | Pharmaceutics | 2021 | | 10.3390/pharmaceutics13081188 http://dr.rgf.bg.ac.rs/s/repo/item/0005481 Дигитални ре ...
... Knutson 3 , Jelena B. Ðoković 1, Aleksandar Kremenović 4 , Vladimir D. Dobričić 5, Danijela V. Randjelović 6, Ivana Pantelić 1 , James M. Cook 3 , Miroslav M. Savić 2 and Snežana D. Savić 1,* ���������� ������� Citation: Mitrović, J.R.; Divović-Matović, B.; Knutson, D.E.; Ðoković, J.B.; ...Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach" in Pharmaceutics, MDPI, Basel, Switzerland (2021). https://doi.org/10.3390/pharmaceutics13081188
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Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study
Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...... improving bioavailability of drugs. J Control Release 260, 202–212. https://doi.org/10.1016/. jeonrel.2017.06.003. Anko, M., Bjelošević, M., Planinšek, O., Trstenjak, U., Logar, M., Grabnar, P.A., Brus, B., 2019. The formation and effect of mannitol hemihydrate on the stability of monocional antibody ...
... mannitol 5% (M 5%), mannitol 10% (M 10%), sucrose 10% (S 10%), sucrose and mannitolin ratio 2:1 in total concentration 10%(S+M2 + 1 10%), sucrose and mannitol in ratio 3:2 in total concentration 10% (S+M 3 + 2 10%), sucrose and mannitol in ratio 1:1 in total concen- tration 10% (S+M 1 + 1 10%) ...
... 6% (S+M 2 + 1 6%). In second lyophilization (lyophili- zation-2) following excipients were added in total concentration 10%: sucrose (S), sucrose and mannitol in ratio 1:1 (S+M 1 + 1), sucrose and mannitol in ratio 3:2 (S+M 3 + 2), trehalose (T), trehalose and mannitol in ratio 1:1 (T+M 1 + 1) ...Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study" in European Journal of Pharmaceutical Sciences, Elsevier BV (2023). https://doi.org/10.1016/j.ejps.2023.106557
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Classification of Neolithic Ceramics and Clays According to Their Morphological Characteristics
Gajić Kvaščev Maja, Svoboda V., Jančić-Heinemann R., Dimitrijević M., Milovanović Dragan, Polić Radovanović Suzana (2012)Gajić Kvaščev Maja, Svoboda V., Jančić-Heinemann R., Dimitrijević M., Milovanović Dragan, Polić Radovanović Suzana. "Classification of Neolithic Ceramics and Clays According to Their Morphological Characteristics" in Mediterraneum Meeting Use of Multivariate Analysis and Chemometrics in Cultural Heritage and Environment-CMA4CH 2012, Rome, Italy:Rome University, La Sapienza (2012)
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Contemporary methods in long range and In Situ Material definition at various locations of Cultural Heritage significance
Srećković Milesa, Barr M. Amy, Kričak Lazar, Ostojić Stanko, Polić Suzana, Dragović Magdalena, Čučaković Aleksandar (2017)Srećković Milesa, Barr M. Amy, Kričak Lazar, Ostojić Stanko, Polić Suzana, Dragović Magdalena, Čučaković Aleksandar. "Contemporary methods in long range and In Situ Material definition at various locations of Cultural Heritage significance" in Zbornik izvoda i izabranih radova Prvog nacionalnog naučno stručnog skupa MULTIDISCIPUNARNI PRISTUP KULTURNOJ BAŠTINI, SAVREMENIM MATERIJALIMA I TEHNOLOGIJAMA, NANT 2017, Beograd :Centralni Institut za konzervaciju, Naučno društvo za razvoj i afirmaciju novih tehnologija (2017): 84-94