Претрага
124 items
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Antioxidant and antimicrobial activity of some tetradentate Schiff bases and their Cu (II) complexes
Aleksandar Mijatović, Milan Nikolić, Snežana Spasić, Aleksandra N. Žerađanin, Kristina Joksimović, Aleksandar Lolić, Rada Baošić (2020)Šifove baze i njihovi Cu(II) kompleksi su poznati po svojoj biološkoj aktivnosti. U ovom radu proučavana je antibakterijska aktivnost protiv gram-negativnih sojeva Escherichia coli, Pseudomonas aeruginosa i Staphilococcus piogenes, kao i Gram-pozitivnih Staphilococcus piogenes i Pseudomonas aeruginosa, zajedno sa antifungalnim dejstvom protiv Musperg strainilusa, A. Takođe, tehnički jednostavni i brzi testovi kao što su ABTS, HORAC i ORAC korišćeni su za ispitivanje antioksidativne aktivnosti kako bi se uporedili dobijeni rezultati sa različitim tipovima testova. Uprkos tome što je princip ...Aleksandar Mijatović, Milan Nikolić, Snežana Spasić, Aleksandra N. Žerađanin, Kristina Joksimović, Aleksandar Lolić, Rada Baošić. "Antioxidant and antimicrobial activity of some tetradentate Schiff bases and their Cu (II) complexes" in XIII Conference of Chemists, Technologists and Environmentalists of Republic of Srpska, University in Banjaluka, Faculty of Technology (2020)
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In vitro and in silico study of the biological activity of tetradentate Schiff base copper(II) complexes with ethylenediamine-bridge
Aleksandar Mijatović, Nevenka Gligorijević, Dušan Ćoćić, Snežana Spasić, Aleksandar Lolić, Sandra Aranđelović, Milan Nikolić, Rada Baošić (2023)The biological activity of six structurally similar tetradentate Schiff base copper(II) complexes, namely [Cu (ethylenediamine-bis-acetylacetonate)] (CuAA) and five derivatives where two methyl groups are replaced by phenyl, (CuPP), CF3 (CuTT) or by mixed groups CH3/CF3 (CuAT), Ph/CF3 (CuPT), and Ph/CH3 (CuAP) has been investigated. The set of antioxidant assays was performed, and the results were expressed as IC50 and EC50 values. The series of complexes showed interesting bioactivity and were investigated for the determination of antioxidant, antifungal, antimicrobial, and ...Aleksandar Mijatović, Nevenka Gligorijević, Dušan Ćoćić, Snežana Spasić, Aleksandar Lolić, Sandra Aranđelović, Milan Nikolić, Rada Baošić. "In vitro and in silico study of the biological activity of tetradentate Schiff base copper(II) complexes with ethylenediamine-bridge" in Journal of Inorganic Biochemistry, Elsevier BV (2023). https://doi.org/10.1016/j.jinorgbio.2023.112224
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In vitro and in silico study of the biological activity of tetradentate Schiff base copper(II) complexes with ethylenediamine-bridge
Aleksandar Mijatović, Nevenka Gligorijević, Dušan Ćoćić, Snežana Spasić, Aleksandar Lolić, Sandra Aranđelović, Milan Nikolić, Rada Baošić (2023)The biological activity of six structurally similar tetradentate Schiff base copper(II) complexes, namely [Cu(ethylenediamine-bis-acetylacetonate)] (CuAA) and five derivatives where two methyl groups are replaced by phenyl, (CuPP), CF3 (CuTT) or by mixed groups CH3/CF3 (CuAT), Ph/CF3 (CuPT), and Ph/CH3 (CuAP) has been investigated. The set of antioxidant assays was performed, and the results were expressed as IC50 and EC50 values. The series of complexes showed interesting bioactivity and were investigated for the determination of antioxidant, antifungal, antimicrobial, and cytotoxic ...Aleksandar Mijatović, Nevenka Gligorijević, Dušan Ćoćić, Snežana Spasić, Aleksandar Lolić, Sandra Aranđelović, Milan Nikolić, Rada Baošić. "In vitro and in silico study of the biological activity of tetradentate Schiff base copper(II) complexes with ethylenediamine-bridge" in Journal of Inorganic Biochemistry, Elsevier BV (2023). https://doi.org/10.1016/j.jinorgbio.2023.112224
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Synthesis, characterization, biomolecular interactions, molecular docking, and in vitro and in vivo anticancer activities of novel ruthenium(III) Schiff base complexes
Milica Međedović, Aleksandar Mijatović, Rada Baošić, Dejan Lazić, Žiko Milanović, Zoran Marković, Jelena Milovanović, Dragana Arsenijević, Bojana Stojanović, Miloš Arsenijević, Marija Milovanović, Biljana Petrović, Ana Rilak Simović (2023)In order to discover new anticancer drugs, novel ruthenium(III) complexes [Ru(L)Cl(H2O)], where L is tetradentate Schiff base bis(acetylacetone)ethylendiimine (acacen, 1), bis(benzoylacetone)ethylendiimine (bzacen, 2), (acetylacetone)(benzoylaceton)ethylendiimine (acacbzacen, 3), bis(acetylacetone)propylendiimine (acacpn, 4), bis(benzoylacetone)propylendiimine (bzacpn, 5) or (acetylacetone)(benzoylaceton)propylendiimine (acacbzacpn, 6), were synthesized. The complexes 1 – 6 were characterized by elemental analysis, molar conductometry, and by various spectroscopic techniques, such as UV–Vis, IR, EPR, and ESI-MS. Based on in vitro DNA/BSA experiments, complexes 2 (bzacen) and 5 (bzacpn) with two aromatic rings showed ...Milica Međedović, Aleksandar Mijatović, Rada Baošić, Dejan Lazić, Žiko Milanović, Zoran Marković, Jelena Milovanović, Dragana Arsenijević, Bojana Stojanović, Miloš Arsenijević, Marija Milovanović, Biljana Petrović, Ana Rilak Simović. "Synthesis, characterization, biomolecular interactions, molecular docking, and in vitro and in vivo anticancer activities of novel ruthenium(III) Schiff base complexes" in Journal of Inorganic Biochemistry, Elsevier BV (2023). https://doi.org/10.1016/j.jinorgbio.2023.112363