Modeling of Sorption and Degradation of selected Pharmaceuticals: case study of Belgrade Groundwater Source

Item

Dimkić, Milan

The application of a mathematical model that analyzes the transport of selected pharmaceuticals from the Sava River to a corresponding radial collector well at Belgrade’s groundwater source is assessed. The occurrence of the selected pharmaceuticals in surface water and the corresponding well was monitored from 2009 to 2015. The pharmaceuticals selected for the present study are carbamazepine, trimethoprim, and metamizole metabolites 4-AAA and 4-FAA. Transport is analyzed based on experimental data (sorption isotherms) and a field tracer experiment that includes injection of the selected pharmaceuticals. The analysis shows that sorption of carbamazepine is relatively low and that this pharmaceutical does not degrade under the studied conditions, so it is not possible to accurately determine the degradation half life. Trimethoprim is detected in the Sava River with an average concentration 8.5 ng/L, but there is no positive detection in well Rb-16. The average concentration of 4-AAA in the surface water is 34 ng/L and of 4-FAA 13 ng/L. The average concentrations of 4-FAAand 4-AAA in the groundwater are in the range from 1 and 1.85 ng/L. The objective of the research is to use an existing hydrogeologic model and apply a transport model to determine the minimum degradation half-life of the investigated pharmaceuticals.

Цитирање: Dimkić, Milan et al., “Modeling of Sorption and Degradation of selected Pharmaceuticals: case study of Belgrade Groundwater Source” у Geološki anali Balkanskoga poluostrva(78).

Contributor

sr Đerić, Nevenka

Creator

sr Dimkić, Milan
sr Kovačević, Srđan
sr Pušić, Milenko
sr Dotlić, Milan

Date

sr 2017

Identifier

sr 10.2298/GABP1778047D

Publisher

sr University of Belgrade – Faculty of Mining and Geology,Department of Regional Geology and Department of Palaeontology

Source

sr Geološki anali Balkanskoga poluostrva

Subject

sr degradation
sr half-life
sr pharmaceuticals
sr sorption
sr model

Abstract

sr The application of a mathematical model that analyzes the transport of selected pharmaceuticals from the Sava River to a corresponding radial collector well at Belgrade’s groundwater source is assessed. The occurrence of the selected pharmaceuticals in surface water and the corresponding well was monitored from 2009 to 2015. The pharmaceuticals selected for the present study are carbamazepine, trimethoprim, and metamizole metabolites 4-AAA and 4-FAA. Transport is analyzed based on experimental data (sorption isotherms) and a field tracer experiment that includes injection of the selected pharmaceuticals. The analysis shows that sorption of carbamazepine is relatively low and that this pharmaceutical does not degrade under the studied conditions, so it is not possible to accurately determine the degradation half life. Trimethoprim is detected in the Sava River with an average concentration 8.5 ng/L, but there is no positive detection in well Rb-16. The average concentration of 4-AAA in the surface water is 34 ng/L and of 4-FAA 13 ng/L. The average concentrations of 4-FAAand 4-AAA in the groundwater are in the range from 1 and 1.85 ng/L. The objective of the research is to use an existing hydrogeologic model and apply a transport model to determine the minimum degradation half-life of the investigated pharmaceuticals.

Date Available

sr 47

Date Created

sr 59

Date Accepted

sr 4

Date Copyrighted

sr 7

Date Submitted

sr NULL

Date Issued

sr 78

Date Modified

sr 1

Spatial Coverage

sr Belgrade

Provenance

sr č292

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